Synthesis Methods

General Resources

Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy

Cochrane Handbook for Systematic Reviews of Interventions

Collaboration for Environmental Evidence (CEE) Guidelines and Standards for Evidence Synthesis in Environmental Management

EPPI Centre Publications on Systematic Review/Evidence Synthesis Methodology

Health Evidence™‘s Quality Assessment Tool for Systematic Reviews designed for use in public health.

Systematic Review Toolbox

SYstematic Review Center for Laboratory animal Experimentation (SYRCLE) Tools and Guidelines provides guidance on how to design, plan and conduct your own systematic reviews (and meta-analysis) of animal studies.

Synthesis Registration

PROSPERO is an international prospective register of systematic reviews

Quality Appraisal and Reporting of Reviews Tools

AMSTAR measurement tool to assess the methodological quality of systematic reviews

MECIR (Cochrane) and MEC2IR (Campbell Collaboration) standards for the conduct and reporting of reviews

PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses

RAMESES reporting standards for realist synthesis and meta narrative reviews

ROBIS tool for assessing the risk of bias in systematic reviews

ROSES reporting standards for systematic evidence syntheses

GRADE Working Group has developed a common, sensible and transparent approach to grading quality (or certainty) of evidence and strength of recommendations.

Software Tools

Covidence is a screening and data extraction tool for streamlining the production of standard intervention reviews.

EPPI-Reviewer is web application that enables management of the entire lifecycle of a review in a single location by enabling users to be able to upload studies for screening, complete keywording and data extractions and analyse the results over the internet.

Rayyan QCRI software assists with review screeening

RevMan assists in the preparation of protocols and full reviews, including text, characteristics of studies, comparison tables, and study data. It can perform meta-analysis of the data entered, and present the results graphically.

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